Which of these following specific immune cells produce cytokines, which facilitate various immune reactions?

Helper T-cells produce cytokines, which facilitate the actions of B-cells and Cytotoxic T-cell. B-cells are responsible for producing immunoglobulins or antibodies while cytotoxic cells directly attack and destroy pathogens. Helper T-cells, cytotoxic cells and B-cells are all antigen-specific immune cells. Macrophage cells are part of non-specific innate immune system which engulf and destroy bacteria and cellular debris during infection and injury.