The meaning of trans- as “across” can be discerned based on vocabulary words like transport (carry across), translate and transfer (both meaning to bear or carry across), transgender (across gender), transition (crossing or going across), transduce (to convert across forms, e.g., of energy), etc. All these share the common prefix meaning of across or from one place or thing to another. One prefix meaning “change” is meta- (e.g., metamorphosis). Port- as in “portable” means carry. A prefix meaning “different” is hetero- (e.g., heterosexual, heterogeneous, heterocyclic, heteromorphic).